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Description

Firstly, we evaluated the cellular functions (Gene Ontology term (GO terms)) over-represented in the differential proteomic dataset

However, while technical limitations may exist regarding adequate GSH rescue, we cannot rule out non-canonical and non-enzymatic functions of GCLC contributing to lipid-related phenotypes

In addition, due to the long-acting properties of YEZTUGO, alternative forms of PrEP should be considered following discontinuation of YEZTUGO for those individuals with HIV-1 negative status who are at continuing risk of HIV-1 acquisition and initiated within 28 weeks of the last YEZTUGO injection [see Warnings and Precautions (5.3)]