dosage b12 injection and Frequency: 7 Guidelines for Adults Vitamin B12 Injections (Cyanocobalamin Injections)

Felzartamab (from I-Mab), already approved for treating membranous nephropathy, is undergoing trials for additional diseases

As discussed, GLP-1 therapy creates a real risk of B12 depletion over time

Additional at-risk groups include: Vegans and strict vegetarians , who may have low dietary B12 intake People with autoimmune conditions , including pernicious anaemia or type 1 diabetes Individuals with gastrointestinal conditions such as Crohn's disease or coeliac disease, which impair nutrient absorption People who have undergone bariatric surgery , which can significantly reduce B12 absorption Long-term users of proton pump inhibitors (PPIs) or H2-receptor antagonists , which reduce gastric acid and impair B12 release from food Those with a family history of either pernicious anaemia or diabetes For these groups, simultaneous monitoring of B12 status and glycaemic markers is particularly important to avoid diagnostic errors

Uncertainty is high in early phase research, so not every trial pans outbut the potential trade-offs are sometimes worth it for those hit hardest by SSRIs/SNRIs