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doi: 10.1016/j.pupt.2023.102284, PMID: [DOI] [PubMed] [Google Scholar] 46

MATERIALS AND METHODS Formalin-induced nociceptive behavioral test The time-effect curves of the control, morphine, and BPC-157 (from 10 to 40 g/kg) groups for the flinching response in the formalin test are shown in Figure 1

Together, these factors contribute to the formation and maintenance of the BBB by increasing expression of TJ proteins, that form a tight seal between endothelial cells and prevent the uncontrolled passage of substances between the peripheral blood and CNS