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The 12-month window between recommendation and enforceable rule is where preparation matters most supply chain and prescriber relationships take time to build and most won't start until it's too late

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When present, side effects are typically mild and transient, potentially including slight drowsiness if administered too early (easily resolved by timing adjustment), mild headaches during initial adaptation in some individuals (usually resolving within days), temporary vivid dreams as sleep architecture normalizes, or rare reports of mild dizziness upon waking in sensitive individuals