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10.1186/s12872-024-04232-z 62 YanX.WangX.ZhangJ.MingZ.ZhangC.MaP.et al (2024)

Adipocytes, which act as glucose sensors [145], senses impaired GLUT4-mediated glucose uptake and release adipocytokines (such as retinol-binding protein 4, RBP 4) to prevent glucose uptake by skeletal muscle and improve hepatic glucose output through insulin signalling blockade [146]

Mental health conditions such as anxiety or depression, as well as fatigue or poor nutrition, can intensify cravings and make withdrawal more difficult

Recent studies have highlighted that CD8 + T cells exhibit selective depletion in the duodenum of patients with ALD, resulting in compromised intestinal barrier function and exacerbation of ALD pathology