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The addition of sodium selenate to metformin is able to restore the hepatic GSH back to normal levels in a type 2 diabetes model which was achieved by feeding the rats with high-fat, high-fructose diet for 8 weeks followed by a low dose of STZ [102]

Effects of curcumin on apoptosis and oxidoinflammatory regulation in a rat model of acetic acid-induced colitis: the roles of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase