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In a recent study, 83% of participants with symptoms of insomnia carried genetic SNPs that decrease DAO production

[20] Treatment of megaloblastic anemia with concurrent vitamin B 12 deficiency using B 12 vitamers (including cyanocobalamin), creates the possibility of hypokalemia due to increased erythropoiesis (red blood cell production) and consequent cellular uptake of potassium upon anemia resolution

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People with stomach and intestinal conditions such as celiac disease and Crohns disease may struggle to absorb enough B12 from their food