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Redox disturbances and skeletal muscle fatigue: in vitro and in situ animal studies As discussed throughout this chapter, it is clear that production of ROS increases in contracting skeletal muscle and animal studies provide convincing evidence that ROS contribute to muscle fatigue induced by prolonged muscular contractions (313, 324)

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The most commonly used modern extraction techniques for obtaining extracts include ultrasonic (UAE), microwave (MAE), pressurized fluid (PLE) and supercritical fluid extraction (SCFE)

Mutations in UBQLN2, which encodes a ubiquitin-like protein involved in shuttling ubiquitinated substrates to the proteasome, are linked to ALS and FTD