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Description

Nature 509 , 439446 (2014)

A recent drug screening also identified a class I HDAC inhibitor, Vorinostat, as an inducer of ferroptosis in small cell lung cancer (SCLC) and isocitrate dehydrogenase ( IDH1/2 )-mutant brain tumors, suggesting an unique vulnerability that is regulated by histone or non-histone acetylation (84)

Among such processes, glycolysis and polyol pathway are probably the best studied examples, as they are well-known sources of carbohydrate-derived RCS