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Previous genetic studies have shown that conditional knockout of Ctnnb1 in the skin impedes the transition of hair follicles from the resting phase to the growth phase, leading to arrested hair growth ( Ctnnb1 is significantly upregulated in anwuligan-treated HFSCs, but this effect was not observed in skin tissues

The study reported lower risks for several cancers, including hepatocellular, colorectal, breast, and prostate cancers, though it did not find a significant reduction in lung cancer risk.25 So the honest answer is this: current human evidence does not show that NAC causes cancer, but animal and mechanistic research suggests NAC could behave differently depending on cancer type, disease stage, dose, and treatment context

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doi: 10.1002/nbm.4706