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Additionally, GHK demonstrated the ability to reverse the expression of various genes, most notably, the gene signature of COPD

Subsequent analysis verified that Epitalon exhibits epigenetic action by specifically binding to the CAG region of DNA, which serves as a methylation target for plant cytosine methyltransferases

Observations in murine models of GHRH gene ablation point to possible normalization of growth indicators, including body weight, bone length, and lean mass, with concurrent increases in pituitary RNA and GH mRNA levels

DECLARATION OF INTEREST: The authors declare that they have no conflicts of interest