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The spread of dihedral angles in beta-pleated sheets is much larger than in alpha-helices and especially in alpha-helix cores, indicating the higher plasticity of beta-structures

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Boelens PG, Houdijk AP, Fonk JC, Nijveldt RJ, Ferwerda CC, Von Blomberg-Van Der Flier BM, et al

Those observations suggested that the role of COX-1 in NAFLD is a subject of controversy, contingent upon complex molecular mechanisms influenced by functional cell types and extracellular stress