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The medication works well for patients whose weight gain relates to mood, stress eating, or food reward sensitivity

Cyanocobalamin, by contrast, requires enzymatic conversion in the liver and tissues to become active

Do not use it if the solution appears cloudy or contains particles

According to long-term safety data published in NIH journals tracking patients for up to 10 years, the most common side effects include headache (19%), injection site reactions (8%), back pain (5%), and fatigue (5%)all typically mild and transient. Safety Profile Comparison: The FDA safety review found that serious adverse events occurred in only 7% of patients over extended treatment periods, with most unrelated to Nucala severe asthma therapy