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During IDD, ECM destruction is accelerated by increased pro-inflammatory cytokines that promote chemotaxis, angiopoietins, and additional cytokine release to maintain an ongoing inflammatory response mediated by ILs, TNFs, interferon (IFN)-c, prostaglandin E2 (PGE-2), and other chemokines

Mittler R, Kim Y, Song L, Coutu J, Coutu A, Ciftci-Yilmaz S et al (2006) Gain-and loss-of-function mutations in Zat10 enhance the tolerance of plants to abiotic stress

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