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Recent advancements in prodrug design have focused on integrating these strategies with delivery systems like liposomes, micelles, and polymerosomes to further improve targeting and reduce side effects

In contrast to conventional bioconjugation strategies or genetic encoding of noncanonical amino acids 73,74 , we have demonstrated that dual functionalized bioconjugates can be easily obtained in situ and in one-pot with high efficiency, making it a user-friendly option also for non-chemists

Then, they induced ferroptosis in the senescent cells to find they were far more sensitive to the cell death pathway than young, healthy cells

Lim and Son, 2020