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Nature medicine 2016;22, 7883, doi: Schoenwaelder, S

The MAPK family includes three major subgroups, extracellular signal regulated kinase (ERK), p38 MAPK (p38), and c-Jun N-terminal kinase/stress activated protein kinase (JNK)

Stimulated by gentamicin and other poisons, TLR4 on KCs surface is activated, and TNF-, IL-6 and other pro-inflammatory factors are secreted through MyD88-dependent pathway (Yang et al., 2022