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National Heart, Lung, and Blood Institute
Lorentzon 1 1 University of Gothenburg, Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Osteoporosis Centre, Gothenburg, Sweden, 2 MRC Lifecourse Epidemiology Centre, University of Southampton,, Southampton, United Kingdom, 3 Mary McKillop Institute for Health Research, Australian Catholic University, Melbourne, Australia, 4 Division of Clinical Medicine, School of Medicine and Population Health, University of Sheffield,, Sheffield, United Kingdom, 5 Mary McKillop Institute for Health Research, Australian Catholic University,, Melbourne, Australia, 6 MRC and Arthritis Research UK Centre for Integrated Research in Musculoskeletal Ageing, Mellanby Centre for Musculoskeletal Research, Sheffield, United Kingdom, 7 Centre for Metabolic Bone Diseases, University of Sheffield, Sheffield, United Kingdom Objectives : FRAXplus allows adjustment of FRAX fracture probabilities for additional clinical information [currently, recency of osteoporotic fracture, high dose oral glucocorticoids, duration of type 2 diabetes mellitus, lumbar spine (LS) BMD, trabecular bone score (TBS), falls history in previous year, or hip axis length (HAL)]
So the protocol sets the dose to land GHK-Cu in a sensible daily range (~1.67 mg), and the three recovery/anti-inflammatory peptides ride along at their lower 0.33 mg each
