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Currently, there is a phase 1 clinical trial to evaluate daratumumab in decreasing circulating antibodies in sensitized recipients awaiting heart transplantation (ClinicalTrials.gov, NCT04088903)

The previous studies of our team found that elemene enhances the sensitivity of tumor cells to chemotherapeutic agents and has the potential to be a novel drug for multidrug-resistant cells, effectively preventing the proliferation, apoptosis, and metastasis of cancer [16,17,18,19]

Other studies found that stevia had no effect, though all were done for shorter periods of time

doi: 10.1016/j.jnutbio.2015.06.005 32 XuDHuMJWangYQCuiYL