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Through laboratoryexperimentationon various animals, including rodents, pigs, dogs, and humans, the unique mechanism of AOD-9604 has been identified, which primarily stimulates the release of fat from adipose tissue, inhibits the accumulation of new fat in adipocytes, and promotes fat oxidation

NNMT activity is elevated in adipose tissue and linked to reduced NAD+ availability, impaired mitochondrial function, and metabolic inflexibility