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Reviewer information Nature Reviews Nephrology thanks A

While occasional moderate consumption probably does not negate treatment benefits entirely, heavy drinking during active healing protocols undermines the process

Subsequently, during proliferative and remodeling phases, TIMP expression increases in coordination with new matrix deposition, preventing premature degradation of nascent collagen and elastic fiber networks

However, given the importance of IL-7 in that process and how IGF-I potentiates the actions of IL-7 in pro-B cell expansion[166], a similar influence on T cells seems likely