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Ginsenoside Rb1, an HO-1 inhibitor, effectively inhibits ferroptosis and significantly improves the clinical symptoms of sepsis

Usefulness of one-point plasma SN-38G/SN-38 concentration ratios as a substitute for UGT1A1 genetic information after irinotecan administration

A successful pH-sensitive mutant would exhibit a K_D comparable to the wild-type antibody at neutral pH to ensure cell surface binding, but a significantly weakened K_D (markedly increased k_off rate) at acidic pH to facilitate rapid dissociation in the lysosome and enable efficient receptor recycling [76]

Additionally, separate observations were conducted on the behavioral effects of reserpine, a drug that depletes monoamine neurotransmitters, when administered in combination with different doses of DOV 102,677