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132 Dehydrocostus lactone exerts different pharmacological benefits, including pro-apoptotic, 133 anti-proliferative, 134 anti-fibrotic, 135 and anti-inflammatory

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It also supported cell survival and inhibited mitochondrial cytochrome c release, thereby suppressing the intrinsic apoptotic pathway, as evidenced by reduced caspase-3 activation

An irreversible axonal injury with demyelination occurs from the beginning, with a steady accumulation of damage to the CNS over time, resulting in irreversible failure and disease development [1]