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Epidemiology CD is one of the most common autoimmune disorders, with a reported prevalence of 0.51% of the general population (Table 1), with the exception of areas showing low frequency of CD-predisposing genes and low gluten consumption (e.g., sub-Saharan Africa and Japan) [7,8,9,10,11,12,13]

Collectively, dysregulated l-Arg metabolism is the underlying cause of NO deficiencies, oxidative stress, and vascular aging

At present, the commonly used analgesic drugs in clinical practice are opioid analgesics and non-steroidal anti-inflammatory drugs, which often lead to dependence and addiction

Oropharyngolaryngeal manifestations in severe toxic epidermal necrolysis: a single-centers retrospective case series