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The TIMP was added solely based on the concerns raised by the IRB, and this motor test will mainly be used as a tool for the DSMB when deciding whether the study should continue or not

These small unmyelinated C-fibres and thinly myelinated A-fibres are the primary fibres affected in diabetic peripheral neuropathy, sarcoidosis-associated neuropathy, and other small fibre neuropathy conditions, making their regeneration a central focus of ARA-290 research