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Description

Irreversible cell cycle arrest leads to cell senescence, which further expedite AKI-CKD progression by altering the microenvironment through their secreted factors

Methods Strains and plasmids The Saccharomyces cerevisiae strain ( MAT cys4::KanMX his31 leu20 lys20 ura30 ), used as a host for the CBS variant library, was derived from the yeast knockout collection [51]