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Description

In addition, we unexpectedly observed that KU-57788 dose-dependently downregulated the protein expression of GPX4, FTH1 and TFR2 (Fig

The rationale is mechanistic extrapolation, not demonstrated synergy

Comprehensive Meta-Analysis Version 4

The growth inhibitory effect of ACA could be rescued by inhibitors of autophagy (bafilomycin A1 and chloroquine) and ferroptosis (liproxstatin-1 and ferrostatin-1), but not by inhibitors of necrosis (NSA) or apoptosis (Z-VAD-FMK) (Supplementary Fig