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Zinc, which contributes to normal cognitive function, normal macronutrient metabolism, and the protection of cells from oxidative stress

Furthermore, changes in TMAO levels have been found in metabolic diseases such as fatty liver and hyperlipidemia, suggesting that lipid metabolism mediated by gut microbiota plays an important role in the occurrence and development of diseases [162, 163]

A 2008 study published in the Journal of Medicinal Chemistry demonstrated metabolic effects in rodent models at 50mg/kg, which led early researchers to extrapolate human-equivalent doses between 50100mg daily

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