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38 Iron overload Although iron is a helpful component of the human body and the major micronutrient in the human diet, involved in crucial cellular functions and metabolic processes, excessive iron increases the production of ROS, leading to cell dysfunction or death, tissue damage, and organ disease

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The choice between variants depends on goals: systemic anabolism favors IGF-1 LR3, while targeted local effects or minimizing systemic exposure favors IGF-1 DES