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Ren et al

Considering the unique functional roles of UA (the end product of purine catabolism) as both antioxidant and pro-oxidant, the homeostatic balance of UA appears to play a vital role of regulatory functions in not only the AODS but also the KYN pathway

In endothelial cell models, BPC-157 enhanced ERK1/2 phosphorylation in a dose-dependent manner, increasing cellular proliferation, migration, and vascular tube formation via downstream transcription factors c-Fos, c-Jun, and EGR-1

L., 2010

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