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[DOI] [PubMed] [Google Scholar] 96.Pou S., Pou W., Bredt D., Snyder S., Rosen G

See text for argumentation of FRDA and FECH interactions during heme biosynthesis

Foundational syntheses, such as that reported by Schneede et al (3), have established the enzymatic basis of HCU, emphasized homocysteine as a pathogenic vascular risk factor and summarized the then-standard treatments: i) Dietary methionine restriction