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AOMs that mimic glucose-dependent insulinotropic polypeptide (GIP) Due to the relatively weak insulinotropic effect observed in patients with T2DM, in addition to the preclinical data on GIP receptor (GIPR) agonism in mice with diet-induced obesity, the use of GIPR agonists (GIPRAs) for the treatment of T2DM and obesity was initially viewed with skepticism (74)

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151 Although these studies demonstrated a beneficial effect of the KD on PCOS, they have limitations such as small sample size, broad age range, single-arm design, and a short intervention time interval

Decreased NO production in endothelial cells exposed to plasma from ME/CFS patients