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*Correspondence: Zhidong Liu, [email protected]

doi: 10.1038/s41419-021-03790-w 113 GengNShiBJLiSLZhongZYLiYCXuaWLet al

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The pathogens intricate hydrophobic cell barrier, one of its most crucial defensive mechanisms, prevents many therapies from entering the body (Sarathy et al., 2012)