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(1) Removal of Units When a Generic Drug Is No Longer a Part D Rebatable Drug At 428.203(b)(1), we proposed to codify the policy established in section 40.2.8 of the revised Medicare Part D Drug Inflation Rebate Guidance to exclude from the rebate calculation any units of a generic drug dispensed on or after the date that such generic drug no longer meets the definition of a Part D rebatable drug

R.EasleyJ.YaoQ.et al (2022)

Therefore, accumulation of sorbitol leads to osmotic stress, collapse, and liquefaction of lens fibers resulting in loss of lens transparency (Pollreisz and Schmidt-Erfurth, 2010