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Furthermore, it should be noted that three recently discovered dimeric indole alkaloids namely 17-deacetoxycyclovinblastine, 14,15-didehydrocyclovinblastine, and 17-deacetoxyvinamidine along with five established compounds (vinamidine, leurosine, catharine, cycloleurosine, and leurosidine) exhibited in vitro viability inhibition against the human breast cancer cell line MDA-MB-231 with an inhibitory concentration ranging from 0.73 to 10.67 M (44)

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Finally, It reproduced selected aerobic-exercise-associated metabolic and transcriptional signals in preclinical models

In: Extremophiles in Eurasian ecosystems: ecology, diversity, and applications