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Short Term Complications Short term complications of type 1 diabetes include hypoglycemic and hyperglycemic episodes: Hypoglycemic Episodes Hypoglycemic episodes can occur as a result of: Too much insulin is given for the meal that was eaten Too much insulin was given in the setting of recent exercise Exercise can increase insulin sensitivity Less insulin may be needed Hyperglycemic Episodes Hyperglycemic episodes can occur as a result of: Not enough insulin is given for the meal that was eaten Non-compliance to the insulin regime Diabetic Ketoacidosis (DKA) When blood sugar levels are too high for too long Leads to a buildup of ketones in the body Leads to hyperglycemia and acidosis Serious complication Often requires hospital admission Long Term Complications Long term complications of uncontrolled type 1 diabetes can cause a range of microvascular and macrovascular complications including: Microvascular (related to small blood vessels) Small blood vessels can become damaged by the sustained inappropriately high blood sugar This can lead to: Diabetic Retinopathy (Eyes) - May cause loss of vision in both eyes Diabetic Nephropathy (Kidneys) - May require dialysis Diabetic Neuropathy (Nerves) - Diabetic peripheral neuropathy has a high mortality rate due to infection Macrovascular (related to large blood vessels) High blood sugar can cause plaque formation in blood vessels This can increase the risk of: Cardiovascular Disease Heart Attack (Myocardial Infarction) Stroke Peripheral Vascular Disease (PVD) Type 1 Diabetes with Disordered Eating (T1DE) It is worth being aware of the implications of a patient with type 1 diabetes withholding their insulin injections

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We'll talk about in a bit low adiponectin, elevated leptin, and elevated resistant