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Nat Rev Immunol 10(7):514526 Ramos-Casals M, Brito-Zern P, Lpez-Guillermo A, Khamashta MA, Bosch X (2014) Adult haemophagocytic syndrome

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Approved injection sites for peptides include: Subcutaneous Areas: Lower abdomen (most common) Flank Outer thigh Upper buttock fat pad Upper arm (back of tricep area) Intradermal Areas (For Skin Rejuvenation): Periorbital region Cheeks Forehead lines Jawline Neck Dcolletage Never inject into: Veins Muscle (unless peptide-specific) Near nerves or arteries Inflamed or infected skin How Providers Should Counsel Patients About Peptide Safety Beyond explaining sourcing, injection technique, and expected outcomes, providers should discuss the lifestyle and medical factors that influence safety

Funding AG acknowledges funding from the CICECO-Aveiro Institute of Materials project, with references UIDB/50011/2020 & UIDP/50011/2020, financed by national funds through the FCT/MEC and when appropriate co-financed by FEDER under the PT2020 Partnership Agreement