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In the presence of o -diphenols such as L-dopa (L-3,4-dihydroxyphenylalanine), both the oxy and met forms react enabling the production of o -quinones 4,9

In addition, folate is synthesized and stored as poly-gamma-glutamate forms in plant cells and can be hydrolyzed into mono-glutamic forms by the enzyme gamma-glutamyl hydrolase (GGH), which has an important influence on the cellular homeostasis of folate [1, 24, 28]

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The gut microbiota metabolite capsiate regulate SLC2A1 expression by targeting HIF-1alpha to inhibit knee osteoarthritis-induced ferroptosis