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Diagnostic criteria and treatment of discogenic pain: a systematic review of recent clinical literature

Although the concept of combination synergy is highly dependent on the underlying assumptions (37), according to SynergyFinder 3.0 the synergy scores can be interpreted as follows: from -10 to 10 the interaction is likely to be additive, larger than 10 the interaction is likely to be synergistic, and conversely, if the score in less than -10, then the interaction between the two drugs is most likely antagonistic