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In PD, the M1 phenotype may be induced by -syn aggregates, signaling through Toll-like receptors (TLR), releasing cytokines and neurotoxic molecules that promote cytotoxic responses, leading to persistent neuroinflammation (Li et al., 2021a)

Early-phase clinical trials should assess safety and tolerability in both healthy volunteers and patient populations, supported by systematic monitoring of adverse events

Organ Protection and Systemic Stability : In systemic toxicity and organ injury research, BPC-157 has been observed to protect the liver, pancreas, and kidneys from induced damage

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