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Certain probiotic-rich fermented foods, such as sauerkraut and kimchi, contain appreciable levels of biogenic amines (e.g., histamine and tyramine), which, in susceptible individuals, can trigger headaches or migraines

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Nevertheless, the immunosuppressive signals from LECs can also inhibit immune cell activation, impair effector functions, and promote immune tolerance towards the tumor

However, many other pathologies are associated with AD onset and progression, including decreased glucose metabolism, oxidative stress, neuroinflammation, altered lipid and metabolite composition of the brain, and age- and disease-associated changes in peripheral metabolism (Xu et al., 2016