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Deposition of collagen IV and aggrecan in leptomeningeal arteries of hereditary brain haemorrhage with amyloidosis

Western blot analysis revealed that recombinant CXCL10 treatment sharply increased the levels of p-P65 and IFN in the CXCL10 group, whereas IL18R1 antibody treatment reduced their levels close to those of the control in the 10+18ab group (Fig

Such neuronal changes, or lesions, are characterized by tangles of nerve fibers and the increased presence of -amyloid and hyperphosphorylated tau in the brain, which ultimately leads to a decline in nervous system function