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Increased GH stimulates the liver to produce IGF-1, which mediates muscle growth, fat loss, tissue repair, and anti-aging benefits

Continuous use beyond 12 months should include HbA1c monitoring every 3 months

IGF-1 LR3 is not separately authorized

The FDA label also includes warnings about fluid retention (which can cause edema, joint pain, and carpal tunnel syndrome), glucose intolerance or diabetes, elevated IGF-1 levels that require monitoring, increased risk of neoplasms or abnormal cell growth (because Tesamorelin stimulates the release of growth hormone, it is contraindicated in patients with active malignancy), hypersensitivity reactions, and increased mortality risk in critically ill patients (a class-effect warning related to growth hormone-releasing products generally)