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Several lines of evidence have indicated that cancer cells establish a counteracting effect to high ROS by increasing the level of antioxidant enzymes to modulate the ROS level to be favorable for themselves [14, 44, 45]

10.1016/j.stemcr.2017.08.017 Stem Cell Reports 112 YanJ.StuderL.MckayR

Oxidative DNA damage induced by ROS-modulating agents with the ability to target DNA: a comparison of the biological characteristics of citrus pectin and apple pectin