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[PubMed] Goldstein AL, Kleinman HK

The possible reason for the inconsistent findings can be explained by various factors including cancer type, drug dosage, synergism, bioavailability, patients lifestyle, tendency to take supplements, and the duration of the studies with other variables incorporated (67) (Table 7)

[4] In some individuals, an auto-immune response inhibits the production of a protein called intrinsic factor which is present in normal stomach secretion