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This unexpected finding may be explained by the limited sensitivity of the immunohistochemistry (IHC) technique, which is generally less sensitive than western blotting or ELISA in detecting subtle changes in protein expression levels

If toxic compounds are ingested in large amount, the glutathione stores are depleted

The field of cataract surgery was transformed in 1967 when Charles Kelman introduced the phacoemulsification technique [77], commonly known as "phaco", where the cataractous lens is broken up by an ultrasonic probe, allowing aspiration through a 3-mm incision [78]

It is the regulatory baseline for 503A compounding facilities operating under FDA oversight