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Considering the evidence that suggests a link between VitB12 deficiency and neurodegenerative disease, including AD [121,122,123,124,125], Theiss and co-workers investigated the potential impact of VitB12 on cell lipid composition using SH-SY5Y as a model

While the clinical significance of this interaction remains uncertain, women relying on oral contraceptives for pregnancy prevention should be counseled about the potential for reduced efficacy and may need to consider additional contraceptive methods, particularly during the initial weeks of therapy when gastric emptying delay is most pronounced

However, mitochondrial dysfunction leads to increased ROS levels and has been implicated in AD pathology (Swerdlow and Khan (2004) and Swerdlow et al