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Its mode of action may involve blocking the PI3K signaling pathway to have an anti-inflammatory effect

In experiments, scientists have shown that mice unable to generate glutathione die before birth

doi: 10.3389/fnut.2025.1677749 Received 01 August 2025 Accepted 31 October 2025 Published 21 November 2025 Volume 12 - 2025 Edited by Jianmei Li, Nanjing Normal University, China Reviewed by Xin Geng, First Affiliated Hospital of Kunming Medical University, China Abraham Al Jody, University of Indonesia, Indonesia Ayush Kumar Srivastava, SUNY Potsdam Department of Chemistry, United States Updates Copyright 2025 Wang, Zhang, Wu, Ma, Wang and Sang

For these six subjects, baseline GSH levels were all assigned the same value (the lowest measured GSH/Cr ratio value across all subjects and scans, divided by 2), in order to calculate the absolute change in GSH/Cr ratio relative to baseline