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Holmes, R

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These findings suggest that manoeuvres designed to increase mucosal GSH content may be useful to withstand the lethal consequences of oxidative stress that may contribute to attenuate the activation and recruitment of related factors that participate in the development of IBD, including VCAM-1 and ICAM-1 (Sans et al, 1999)

Note a stronger regenerative response may be seen in animals with anemia of inflammatory disease if there is a concurrent stimulus for erythrocyte production, which can over-ride the inflammatory cytokine-induced suppression