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DellAgli M, Fagnani R, Mitro N, Scurati S, Masciadri M, Mussoni L, Galli GV, Bosisio E, Crestani M, De Fabiani E, Tremoli E, Caruso D

If the abovementioned is occurring, it could mean that IGF-1 administration could also lower glucose levels by suppressing hepatic gluconeogenesis, as well as improving insulin signalling in this organ, leading to IGFBP-1 suppression and overall improvement of the IGF-1/GH/insulin axis

Xu X, Li M, Yu F, Wei Q, Liu Y, Tong J, Yang F

In addition, major malformations of the central nervous system originating from the neural tube, such as caudal regression syndrome, were more prevalent in the offspring of mothers with both type 1 diabetes mellitus and type 2 diabetes