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Discussion and Therapeutic Considerations This case report illustrates that severe intravascular hemolysis [9,1,4,10,7] and methemoglobinemia [9,1,2,11,12,10,13,5,6,8] can occur in a G6PD deficient patient following ingestion of ironcontaining (Fe3+) substances like hematite (geru powder) (Figures 1 & 2)

The HPA axis plays a key role in this connection

Widely recognised as the bodys Master Antioxidant, Glutathione is a potent tripeptide essential for phase II liver detoxification and cellular defense

Lee A, Gu H, Gwon M-H, Yun J-M (2021) Hesperetin suppresses LPS/high glucose-induced inflammatory responses via TLR/MyD88/NF-B signaling pathways in THP-1 cells